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AH 7614 As the first allotetraploid fish in the
2019-07-02
As the first allotetraploid fish in the world, our lab selectively breed the allotetraploid hybrid fish (4nAT, 4n = 200) from the distant hybridization offspring F3 of female Red Crucian Carp (Carassius auratus red var., abbreviated as RCC, 2n = 100) and male Common Carp (Cyprinius carpio L., abbrev
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CaneCPI showed strong inhibitory activity against recombinan
2019-07-02
CaneCPI-4 showed strong inhibitory activity against recombinant falcipain-2 and falcipain-3, with IC values of 11.9±0.4nM and 42.3±0.8nM, respectively (Table 1, Supplementary material). Falcipains are involved in hemoglobin cleavage, with generation of two fractions: the heme and the globin. The hem
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CIC mediated chemoresistance is driven by several factors
2019-07-02
CIC-mediated chemoresistance is driven by several factors. In our quest to learn about these, we examined the crucial mediators identified earlier in the regulation of CSC survival and chemoresistance, such as BCL2, cleaved Caspase-3, COX-2, and macrophages. Interestingly, we observed a significantl
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br Conflicts of interest br Acknowledgments
2019-07-02
Conflicts of interest Acknowledgments Work in the laboratory of SPS is funded by Council of Scientific and Industrial Research (CSIR) Network Project BSC-0111 (INDEPTH) and BSC-0112 (NanoSHE). We are thankful to Director, CSIR-IITR for his constant encouragement and support. We also acknowledg
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During the Lapita period in Tonga the Talasiu site would
2019-07-02
During the Lapita period in Tonga, the Talasiu site would have been an attractive location for human settlement as it overlooked an embayment holding large numbers of sessile and gregarious shellfish close to a fresh water solution channel, with gardening soils immediately inland. However, sea level
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Introduction Breast cancer is a highly prevalent malignancy
2019-07-02
Introduction Breast cancer is a highly prevalent malignancy. There are some recognized risk factors for breast cancer, like early menarche or late menopause, which increase the length of the exposure to hormones, as a result of a higher number of ovarian cycles [1]. Moreover, there is evidence supp
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br Introduction O Methylguanine DNA methyltransferase MGMT i
2019-07-02
Introduction O6-Methylguanine-DNA methyltransferase (MGMT) is a DNA-repair enzyme that specifically transfers alkyl adducts from the O6 position of guanine to the cysteine residue (Cys145) in its active site. In cancer cells, this ability of MGMT disrupts the cytotoxic actions of alkylating antic
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Previous studies reported that combined administration of li
2019-07-01
Previous studies reported that combined administration of licorice/GL and TWHF/TP showed reduced toxicity and equal or even potentiated therapeutic efficacy when treating arthritis (YS et al., 2006, YS et al., 2008, Zhang et al., 2007). Our findings that GL reduced exposure to TP in rats confirmed t
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The mean values of the ischiopubic index in the current
2019-07-01
The mean values of the ischiopubic index in the current study were 94.28±9.18 in male and 107.96±11.54 in female. In this tlr inhibitor study, the length of the pubis in male and that in female were 82.10±7.21 mm and 87.35±7.78 mm, respectively, and the length of the ischium was 87.51±7.95 in men a
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Roughly years have gone by
2019-07-01
Roughly 15 years have gone by since the identification of the main characters involved in the interplay of the RANK–RANKL system. This gave rise to the race for elucidating their biological role . In those years, in vivo silencing experiments for both Receptor Activator of Nuclear Factor κ B (RANK)
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br Case report We report on a year old
2019-07-01
Case report We report on a 28-year-old male without any past medical history. After a minor work accident (professional mechanic) he noticed significant pain in his left knee. The pain increased over time and a radiograph was taken. It showed minor bone resorption at the neck of the left proximal
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br Results br Discussion Atrial fibrillation is widely
2019-07-01
Results Discussion Atrial fibrillation is widely recognized as the most common sustained arrhythmia. The risk of AF development may be determined by evaluating the patients’ age, sex, underlying ptio of disease, other medical illnesses, and echocardiographic findings. However, better predicto
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Aminoallyl-dUTP - Cy3 Por otro lado cabe subrayar que esta e
2019-07-01
Por otro lado, cabe subrayar que esta “elegía” de Pellicer se asemeja al género precolombino del icnocuicatl, los “Canto[s] de desolación, de orfandad” (Garibay 1992: 89). Según Garibay, estos cantos precolombinos “tienen parentesco con las elegías […] de los poetas de Occidente, en que se canta la
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There are major challenges in the estimation of the
2019-07-01
There are major challenges in the estimation of the prevalence of opioid use in Afghanistan. The country has been in a state of war and insurgency for the better part of 40 years; its Forskolin is widely dispersed and often very mobile; it has low levels of literacy; and Afghans are not accustomed
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Doxorubicin Argentina adopta una posici n semejante a los an
2019-07-01
Argentina adopta una posición semejante Doxorubicin los anteriores países, Aborda el principio en la Ley 25675, incorpora un seguro como requisito para cubrir los posibles daños ambientales en las actividades riesgosas, específicamente señala el Artículo 22 de dicha ley. Asimismo, define el daño amb
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