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The importance of social determinants
2019-06-18
The importance of social determinants on population health is widely known. Beyond this recognition, key questions that still need to be addressed include research into how to best address social determinants through intersectoral collaboration. Pillay-van Wyk and colleagues identify this approach a
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br Discussion Intriguingly in a case report about elevation
2019-06-18
Discussion Intriguingly, in a case report about elevation of skeletal enzymes in ultramarathon runners, the CK level reached its peak value one day after the run, had a ∼4-day plateau, and began to decline after a few more days. The sustained increase of plasma CK in this athlete was quite differ
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Two other groups subsequently published further data on
2019-06-18
Two other groups subsequently published further data on iPSCs models of ARVC that have improved our understanding of this disease. Kim et al. developed iPSC models using episomal methods from 2 ARVC patients, as well as with PKP2 mutations . Detailed electrophysiological characterization of mutant
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br Method br Results br Discussion br Conclusions br
2019-06-18
Method Results Discussion Conclusions Conflict of interest Acknowledgments Introduction Cardiac sarcoidosis is a known cause of atrioventricular (AV) block, especially in younger people. Its progression can lead to ventricular tachycardia or heart failure [1]. Steroid therapy or
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br Clinical evidence to support that PES predicts cardiac
2019-06-18
Clinical evidence to support that PES predicts cardiac events in BS Brugada et al. were the first to propose that inducibility of sustained ventricular arrhythmias with PES is useful to identify patients who are at high risk of SCD [3]. During follow-up of patients with spontaneous type 1 Brugada
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Numerous animal studies have demonstrated beyond
2019-06-18
Numerous animal studies have demonstrated beyond doubt that effective inhibition of osteoclastogenesis or osteoclast function significantly reduces metastatic tumour growth in bone [13–20]. Likewise, clinical trials in patients with non-metastatic or metastatic cancers established that treatment wit
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br Introduction Once metastatic breast cancer cells
2019-06-18
Introduction Once metastatic breast cancer order MTT are in the bone marrow, they hijack signals coming from the normal bone remodelling process and promote bone degradation [1]. Bone degradation is caused by osteoclasts, which have the unique property to dissolve bone mineral and degrade the bon
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TEE guidance can also be helpful during pulmonary vein
2019-06-18
TEE guidance can also be helpful during pulmonary vein cryoablation for AF. Kerut et al. [9] described their first 20 cases of cryoablation for AF using TEE and found TEE to have better overall procedural imaging and monitoring for pericardial effusion or thrombus formation. They found TEE monitorin
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Cardiovascular magnetic resonance imaging CMR is
2019-06-18
Cardiovascular magnetic resonance imaging (CMR) is recognized as a versatile, safe, and reproducible technique, allowing for accurate structural and functional assessment of the heart. CMR is the gold standard for ejection fraction measurement [15–17]. Considering the technical limitations of other
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br Conventional mapping and ablation
2019-06-18
Conventional mapping and ablation of ventricular tachycardia Substrate mapping during sinus rhythm Technical issues Conclusion Conflict of interest Introduction By eliminating the arrhythmogenic focus, catheter ablation can be a curative therapy of ventricular tachyarrhythmias (VTA
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Remote monitoring offers ongoing opportunities for managemen
2019-06-17
Remote monitoring offers ongoing opportunities for management from three perspectives: Concept of remote monitoring for trans-4-Hydroxycrotonic acid manufacturer failure Most HF-related hospitalizations are due to fluid accumulation, and careful surveillance of a patient\'s fluid status and symp
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It is noteworthy that in a
2019-06-17
It is noteworthy that in a recent study, Le Scouarnec et al. [199]. estimated the burden of rare coding variation in arrhythmia susceptibility genes among 167 BrS index patients and compared that with 167 individuals ≥65 years old with no history of cardiac arrhythmia. The authors concluded that, ex
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Fourth the enormous investment in
2019-06-17
Fourth, the enormous investment in accessible medicines and medical products without investment in checking their quality is profoundly illogical. WHO estimates that only 7% of sub-Saharan countries had a “moderately functioning MRA”. We cannot expect the world\'s medicine supply to improve without
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A year old female patient was referred to us for
2019-06-17
A 55-year-old female patient was referred to us for GSK621 of an implantable cardioverter-defibrillator (ICD) after cardiac arrest due to idiopathic ventricular fibrillation. As she was young and had no indications for cardiac resynchronization therapy or bradycardia support, she was screened for a
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Seg n Auerbach la parataxis es
2019-06-17
Según Auerbach, la parataxis es un modo primitivo y anticlásico de narrar, típico de la Edad Media, que será sustituido gradualmente por maneras más modernas y finas de describir la realidad. No obstante, en fechas recientes ha vuelto order Fluoxymesterone ser practicada, por ejemplo por una serie d
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