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Introduction Several types of cancers including
2019-05-20
Introduction Several types of cancers, including those originating in the breast, prostate, and lung, have a propensity to metastasize to the bones [1,2]. Bone metastases severely impair skeletal metabolism, and result in important clinical sequelae, such as excruciating chronic bone pain and the s
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The principal difference between BrS and ERS is
2019-05-20
The principal difference between BrS and ERS is related to the region of the ventricle most affected. Epicardial mapping studies in BrS patients report accentuated J waves and fragmented and/or late potentials in the epicardial region of the RVOT [129–131], whereas in ERS only accentuated J waves, p
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Because our patient s native rhythm remained AV block
2019-05-20
Because our patient׳s native rhythm remained 2:1 AV block with a narrow QRS, we attempted HBP as the first-line treatment based on the assumption that His-Purkinje conduction might be preserved. Another benefit of HBP in this patient with CKD is that the use of iodinated buy XL184 media could be av
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br Results Compared to the respective
2019-05-20
Results Compared to the respective untreated groups, the VT duration was shorter in clonidine-treated ETB-deficient rats during phase I and in wild-type rats during phase II (Fig. 1A). Heart rate (HR) increased in both untreated groups, but this response was blunted after clonidine, mainly in ETB
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Bile acids are cholesterol derivatives produced only in the
2019-05-20
Bile acids are cholesterol derivatives produced only in the hepatocytes of the liver. Hepatic bile acid synthesis represents the only quantitatively significant route for cholesterol elimination. Bile acids are amphipathic physiological detergents that facilitate dietary cholesterol, lipid and fat-s
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br Control of visceral leishmaniasis requires access
2019-05-20
Control of visceral leishmaniasis requires access to low-cost, safe, and effective treatment. Amphotericin causes infusion-related fever, rigor, and nephrotoxicity, limiting its use. Ambisome—a liposomal amphotericin manufactured by Gilead—is better tolerated and is effective as a single dose. How
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Si en La virgen de los sicarios la vida crapulosa
2019-05-20
Si en La virgen de los sicarios “la vida crapulosa está derrotando sphingosine 1-phosphate receptor modulator la muerte”, y “anda toda ventiada por Medellín día y noche en su afán haciendo lo que puede, compitiendo con semejante paridera, la más atroz [y] este continuo nacer de niños y el suero oral
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Pero el fuerte del comercio exterior
2019-05-20
Pero el fuerte del comercio exterior argentino no sólo estuvo centrado en la demanda china, también Latinoamérica fue un mercado importante para las exportaciones. En este sentido, Daniel Berrettoni y Mariángeles Polonsky sostienen que fue clave “la importancia y el dinamismo del mercado brasileño c
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On Aug WHO quietly released a
2019-05-20
On Aug 23, WHO quietly released a report that should be essential reading for all. Coming 15 years after the Abuja Declaration by African governments to commit to spending 15% of annual domestic budgets on health, concludes with a stark analysis: “For every US$100 that goes into state coffers in Af
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br The Millennium Development Goals
2019-05-20
The Millennium Development Goals on health have expanded access to basic health interventions to millions of people in low-income and middle-income countries (LMICs). However, access alone will not be sufficient to meet the Sustainable Development Goals (SDGs) if health systems cannot provide high
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In a study of the atrial pacing preference
2019-05-20
In a study of the atrial pacing preference (APP) algorithm, Ogawa et al. [12] randomly programmed pacemakers as APP OFF and APP ON at 3 different settings (8, 16, and 33 cycles). The authors found that the most effective setting differed according to the patient and thus concluded that this therapy
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br Conclusiones br LA REVISTA
2019-05-20
Conclusiones LA REVISTA DE FILOSOFÍA Para la época en que se publicaba la Revista de Filosofía, Cultura, Ciencias y Educación, José Ingenieros lideraba una agrupación nucleada en torno myd88 signaling intereses intelectuales y afinidades personales que recuperaba, aunque con mucha más moderaci
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integrin signaling pathway Chronic myelomonocytic leukemia h
2019-05-20
Chronic myelomonocytic leukemia has been reported as the most prevalent concomitant hematological neoplasm, followed by myelodysplastic, myeloproliferative syndrome, and acute myeloid leukemia; on the other hand, Lymphoproliferative neoplasms were less frequency associated with SM-AHMND. In another
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br Genetic basis Similar to
2019-05-18
Genetic basis Similar to other arrhythmia syndromes, Brugada and early repolarization syndromes are inherited diseases that are usually transmitted in an autosomal-dominant manner [26]. To date, 13 genes have been associated with Brugada syndrome. Loss-of-function mutations in SCN5A, encoding the
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could Sustained AT Fig b B was induced during pacing
2019-05-18
Sustained AT2 (Fig. 1b(B)) was induced during pacing from the coronary sinus. The 3D activation map and the entrainment mapping including PPI from the CTI identified AT2 as a macroreentrant tachycardia circling counter-clockwise around the TA. AT2 was eliminated by CTI ablation. Sustained AT3 (Fig.
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