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Sultan et al retrospectively searched the surveillance epide
2019-06-19
Sultan et al retrospectively searched the surveillance, epidemiology, and end results (SEER) database for patients who were diagnosed with NPC from 1988 to 2006. They compared the clinical features and outcomes of 129 children and adolescents (n and young adults compared with older adults with nasop
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Primary lymphoma of bone is an
2019-06-19
Primary lymphoma of bone is an uncommon clinical entity and accounts for less than 5% of malignant bone tumors, 4–5% of extra nodal lymphoma and less than 1% of all non-Hodgkin\'s lymphoma. Diffuse large-B-cell lymphoma (DLBCL) accounts for the majority of cases of PBL [2]. The varied clinical and h
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The work by Fumiaki Imamura
2019-06-18
The work by Fumiaki Imamura and colleagues in this issue of is a unique attempt to evaluate measures of dietary quality and their trends in most countries worldwide. They used a wide range of data sources, including nationally representative dietary surveys, local surveys, and foods disappearance d
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br An estimated million babies are born preterm annually
2019-06-18
An estimated 15 million babies are born preterm annually. Preterm birth complications account for more than 15% of deaths in children younger than 5 years and survivors often have long-term consequences with respect to their health, growth, and psychosocial functioning. The most beneficial interve
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Lastly it is equally important to mention
2019-06-18
Lastly, it is equally important to mention that the microenvironment and genetic background of the host with a previous history of two independent malignancies may have further facilitated the selective proliferation of a clone with trisomy 11 [9,10], while normal 2-APB suffered proliferative stres
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br Indigenous communities experience some of the
2019-06-18
Indigenous communities experience some of the highest rates of suicide globally, especially among young people. This worrying epidemic has already been shown in Inuit communities of North America and Greenland and the Amazonian groups of Guyana, but recently has been shown to extend to Australian
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The importance of social determinants
2019-06-18
The importance of social determinants on population health is widely known. Beyond this recognition, key questions that still need to be addressed include research into how to best address social determinants through intersectoral collaboration. Pillay-van Wyk and colleagues identify this approach a
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br Discussion Intriguingly in a case report about elevation
2019-06-18
Discussion Intriguingly, in a case report about elevation of skeletal enzymes in ultramarathon runners, the CK level reached its peak value one day after the run, had a ∼4-day plateau, and began to decline after a few more days. The sustained increase of plasma CK in this athlete was quite differ
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Two other groups subsequently published further data on
2019-06-18
Two other groups subsequently published further data on iPSCs models of ARVC that have improved our understanding of this disease. Kim et al. developed iPSC models using episomal methods from 2 ARVC patients, as well as with PKP2 mutations . Detailed electrophysiological characterization of mutant
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br Method br Results br Discussion br Conclusions br
2019-06-18
Method Results Discussion Conclusions Conflict of interest Acknowledgments Introduction Cardiac sarcoidosis is a known cause of atrioventricular (AV) block, especially in younger people. Its progression can lead to ventricular tachycardia or heart failure [1]. Steroid therapy or
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br Clinical evidence to support that PES predicts cardiac
2019-06-18
Clinical evidence to support that PES predicts cardiac events in BS Brugada et al. were the first to propose that inducibility of sustained ventricular arrhythmias with PES is useful to identify patients who are at high risk of SCD [3]. During follow-up of patients with spontaneous type 1 Brugada
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Numerous animal studies have demonstrated beyond
2019-06-18
Numerous animal studies have demonstrated beyond doubt that effective inhibition of osteoclastogenesis or osteoclast function significantly reduces metastatic tumour growth in bone [13–20]. Likewise, clinical trials in patients with non-metastatic or metastatic cancers established that treatment wit
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br Introduction Once metastatic breast cancer cells
2019-06-18
Introduction Once metastatic breast cancer order MTT are in the bone marrow, they hijack signals coming from the normal bone remodelling process and promote bone degradation [1]. Bone degradation is caused by osteoclasts, which have the unique property to dissolve bone mineral and degrade the bon
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TEE guidance can also be helpful during pulmonary vein
2019-06-18
TEE guidance can also be helpful during pulmonary vein cryoablation for AF. Kerut et al. [9] described their first 20 cases of cryoablation for AF using TEE and found TEE to have better overall procedural imaging and monitoring for pericardial effusion or thrombus formation. They found TEE monitorin
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Cardiovascular magnetic resonance imaging CMR is
2019-06-18
Cardiovascular magnetic resonance imaging (CMR) is recognized as a versatile, safe, and reproducible technique, allowing for accurate structural and functional assessment of the heart. CMR is the gold standard for ejection fraction measurement [15–17]. Considering the technical limitations of other
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