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In terms of sensitivity a different situation
2020-07-28
In terms of sensitivity, a different situation occurs when dealing with nerve paralytic substances for which these detection systems are especially intended. It is expected that the detection limit for nerve agents will be from 10−2 to 10−4 mg L−1 in water [27]. At a soman dose of 10−2 mg L−1, the s
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We demonstrate that CLIC CLIC and CLIC are
2020-07-28
We demonstrate that CLIC1, CLIC4 and CLIC5 are the most abundant CLIC transcripts present in the heart. CLIC4 and CLIC5 but not CLIC1 localize to adult cardiac mitochondria. CLIC localization in the GDC-0994 sale was also observed in cardiac tubes of Drosophila melanogaster. Further, we show that C
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Introduction Activation of epidermal growth factor receptor
2020-07-27
Introduction Activation of epidermal growth factor receptor (EGFR)-receptor tyrosine kinases (RTKs) is a key factor in the progression of non-small cell lung cancer (NSCLC). EGFR-RTKs cause proliferation, invasion, metastasis, and angiogenesis, as well as suppress apoptosis, in lung adenocarcinoma
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br Conclusion A combination of two computational techniques
2020-07-27
Conclusion A combination of two computational techniques were applied to study a series of nineteen 7,8-dialkylpyrrolo-[3,2-f] Quinazoline derivatives, not only to generate highly statistical and predictive 3D-QSAR models, but to explore the interaction mechanism between the Quinazoline derivativ
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Orthologues of carotenoid dioxygenases used by humans to pro
2020-07-27
Orthologues of carotenoid dioxygenases, used by humans to produce retinal from beta-carotene, have previously been characterised from the cyanobacteria Synechocystis PCC 6803 and Nostoc PCC 7107 [[11], [12], [13], [14]]. These orthologues are able to convert beta-carotene and apo-8-carotenal into al
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The present work together with our previous
2020-07-27
The present work, together with our previous study, offers a means of conferring collagen-binding integrin-, VWF- and DDR-reactivity upon an inert substrate. GPRGQOGVNleGFO is known to bind not only VWF and DDR2, but also DDR1 and SPARC (Secreted Protein Acidic and Rich in Cysteine) [20,52]. We ther
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br Conclusion br Acknowledgments br Introduction Arsenic As
2020-07-27
Conclusion Acknowledgments Introduction Arsenic (As) is one of the most toxic metals derived from the natural environment in soil, air and well water. It has two oxidative states: a trivalent form, arsenite, and a pentavalent form, arsenate. The inorganic As is more toxic than organic As. A
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br Conclusions AAA is a
2020-07-27
Conclusions AAA is a serious, life-threatening disease with a major socio-economic impact and the rating of aneurysm growth and the risk of rupture are both exponentially related to aneurysm size [1]. Since AAA is associated with high morbidity and mortality, screening programs for AAA detection
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From the theoretical point of
2020-07-27
From the theoretical point of view some rationalizations can be done if the symmetry considerations are included in the calculations. When only configurations are considered all systems of , and symmetry may be treated as a purely axial () ligand field [25], [26]. It means that in the present case i
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This theory allows to use the
2020-07-27
This theory allows to use the Free Gibbs Energy to calculate the probability of transition for a chemical reaction characterized by its rate of reaction proportional to the Cy5 maleimide (non-sulfonated) receptor height of the transition state between the initial state and the intermediate state na
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br Materials and methods br Results br Discussion In this
2020-07-27
Materials and methods Results Discussion In this study, we uncovered a female-specific haplotype-MDD vulnerability association, by which a two-marker haplotype TG of rs4633-rs4680 may link to enhanced MDD risk in females. Female haplotype TG carriers were estimated to have a 9.17-fold incre
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br Materials and methods br Statistical analysis All
2020-07-25
Materials and methods Statistical analysis All statistical analyses were performed using SPSS software version 20. Protein NAD+ data of DNMTs and clinicopathological parameters were collected. Mann-Whitney U Test was used to assess the differential expression of nonparametric data of DNMTs pr
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Conversely to the reduction in
2020-07-25
Conversely to the reduction in restraint-evoked HR increase following the blockade of CRF receptors, Nijsen et al. [28] demonstrated that BNST treatment with a nonselective CRF Laminin 925-933 antagonist enhanced the tachycardia evoked by contextual fear conditioning. Taken together, these results
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The intricate roles and neural systems and
2020-07-25
The intricate roles and neural systems and mechanisms involved in the CRF1 and CRF2 mediation of spontaneous and stress-induced anxiety behavior remain to be defined. Of particular relevance are studies evaluating the behavioral actions of CRF1 and CRF2 receptors separately as well as together. For
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The performance of the qCPA approaches is
2020-07-25
The performance of the qCPA approaches is similar with regards to the derivative properties of CO2 and for mixtures of CO2+self-associating compounds. For CO2+n-alkanes the four-parameter versions of qCPA both perform somewhat better than the three-parameter version. Nevertheless this modest improve
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