• A review by Keung and colleagues summarized cases of

  2019-06-19

  

  A 2002 review by Keung and colleagues summarized cases of hematologic malignancy in patients with KS reported between 1961 and 2002 [3]. They described 12 cases of AML in KS in the literature during that time period. Based on the review of the current literature, we found approximately 10 additional

• The importance of social determinants on population

  2019-06-19

  

  The importance of social determinants on population health is widely known. Beyond this recognition, key questions that still need to be addressed include research into how to best address social determinants through intersectoral collaboration. Pillay-van Wyk and colleagues identify this approach a

• Although the study is of a high quality given the

  2019-06-19

  

  Although the study is of a high quality given the constraints of the case-control design, we question whether it alone provides sufficient evidence for this policy recommendation. Observational studies of ITNs are notoriously fraught with challenges. Even in settings in which randomised trials show

• Sultan et al retrospectively searched the surveillance epide

  2019-06-19

  

  Sultan et al retrospectively searched the surveillance, epidemiology, and end results (SEER) database for patients who were diagnosed with NPC from 1988 to 2006. They compared the clinical features and outcomes of 129 children and adolescents (n and young adults compared with older adults with nasop

• Primary lymphoma of bone is an

  2019-06-19

  

  Primary lymphoma of bone is an uncommon clinical entity and accounts for less than 5% of malignant bone tumors, 4–5% of extra nodal lymphoma and less than 1% of all non-Hodgkin\'s lymphoma. Diffuse large-B-cell lymphoma (DLBCL) accounts for the majority of cases of PBL [2]. The varied clinical and h

• The work by Fumiaki Imamura

  2019-06-18

  

  The work by Fumiaki Imamura and colleagues in this issue of is a unique attempt to evaluate measures of dietary quality and their trends in most countries worldwide. They used a wide range of data sources, including nationally representative dietary surveys, local surveys, and foods disappearance d

• br An estimated million babies are born preterm annually

  2019-06-18

  

  An estimated 15 million babies are born preterm annually. Preterm birth complications account for more than 15% of deaths in children younger than 5 years and survivors often have long-term consequences with respect to their health, growth, and psychosocial functioning. The most beneficial interve

• Lastly it is equally important to mention

  2019-06-18

  

  Lastly, it is equally important to mention that the microenvironment and genetic background of the host with a previous history of two independent malignancies may have further facilitated the selective proliferation of a clone with trisomy 11 [9,10], while normal 2-APB suffered proliferative stres

• br Indigenous communities experience some of the

  2019-06-18

  

  Indigenous communities experience some of the highest rates of suicide globally, especially among young people. This worrying epidemic has already been shown in Inuit communities of North America and Greenland and the Amazonian groups of Guyana, but recently has been shown to extend to Australian

• The importance of social determinants

  2019-06-18

  

  The importance of social determinants on population health is widely known. Beyond this recognition, key questions that still need to be addressed include research into how to best address social determinants through intersectoral collaboration. Pillay-van Wyk and colleagues identify this approach a

• br Discussion Intriguingly in a case report about elevation

  2019-06-18

  

  Discussion Intriguingly, in a case report about elevation of skeletal enzymes in ultramarathon runners, the CK level reached its peak value one day after the run, had a ∼4-day plateau, and began to decline after a few more days. The sustained increase of plasma CK in this athlete was quite differ

• Two other groups subsequently published further data on

  2019-06-18

  

  Two other groups subsequently published further data on iPSCs models of ARVC that have improved our understanding of this disease. Kim et al. developed iPSC models using episomal methods from 2 ARVC patients, as well as with PKP2 mutations . Detailed electrophysiological characterization of mutant

• br Method br Results br Discussion br Conclusions br

  2019-06-18

  

  Method Results Discussion Conclusions Conflict of interest Acknowledgments Introduction Cardiac sarcoidosis is a known cause of atrioventricular (AV) block, especially in younger people. Its progression can lead to ventricular tachycardia or heart failure [1]. Steroid therapy or

• br Clinical evidence to support that PES predicts cardiac

  2019-06-18

  

  Clinical evidence to support that PES predicts cardiac events in BS Brugada et al. were the first to propose that inducibility of sustained ventricular arrhythmias with PES is useful to identify patients who are at high risk of SCD [3]. During follow-up of patients with spontaneous type 1 Brugada

• Numerous animal studies have demonstrated beyond

  2019-06-18

  

  Numerous animal studies have demonstrated beyond doubt that effective inhibition of osteoclastogenesis or osteoclast function significantly reduces metastatic tumour growth in bone [13–20]. Likewise, clinical trials in patients with non-metastatic or metastatic cancers established that treatment wit

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