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All patients engrafted patient Patient
2019-05-31
All patients engrafted; 1 patient (Patient 6) developed secondary graft rejection following an A antigen mismatched graft from a male sibling and went on to receive a VUD HSCT with a female donor. There were no major conditioning related toxicities. Bacterial infections occurred in 6 patients prior
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Idelalisib demonstrates a dual mechanism of action
2019-05-31
Idelalisib demonstrates a dual mechanism of action by inhibiting pro-survival signalling pathways [6], and, like other kinase inhibitors, leads to re-localisation of tumour thrombopoietin receptor agonist by blocking ingress into and promoting egress out of the lymph node into the blood. Release fr
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ZIKV is a flavivirus related to
2019-05-31
ZIKV is a flavivirus related to dengue virus (DENV) and historically has been transmitted by the same mosquito species, (). There is no available treatment or vaccine so disease control is limited to the management of mosquitoes which currently relies on either insecticides or the destruction of la
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The concept of metronomic chemotherapy began in the
2019-05-31
The concept of metronomic chemotherapy began in the 1990s, when Kerbel showed chemotherapeutic agents may be able to target tumor vessel endothelial cells. In 2000, Browder et al demonstrated a more frequent, lower dose of cyclophosphamide, i.e. anti-angiogenic schedule, could induce response in tum
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The presence of an inflammatory
2019-05-31
The presence of an inflammatory infiltrate is associated with poor prognosis in a number of malignancies, including those with a predilection for metastasis to bone. CAFs are capable of promoting, and maintaining an inflammatory environment by recruiting immune cells; in particular monocyte/macropha
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Los tres aspectos se alados del marco
2019-05-31
Los tres aspectos señalados del marco paratextual se encuentran ligados purchase Cy3.5 maleimide las condiciones de producción y de publicación de la novela y allanan el camino de la apropiación y de la subversión textual que realizan sus traductores criollos tras la máscara de la fraternidad de los
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El n mero de correspondiente al segundo
2019-05-30
El número 59 de , correspondiente al segundo semestre de 2014, ofrece la sección Temas y Problemas de Nuestra América, en el que se encuentran artículos relacionados con asuntos de gran relevancia actual. En primer lugar, el texto “Nuevas narrativas constitucionales en Bolivia y Ecuador: el buen viv
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Agosto toma la medida del relato hist rico
2019-05-30
Agosto toma la medida del relato histórico en algunas ocasiones, de la crónica periodística en otras, para obtener una narración que ha llegado a entremezclarse con la realidad, o al menos con una investigación académica bien documentada, al grado tal que es bastante común encontrarla citada en artí
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En Latinoam rica donde se presentan intentos de
2019-05-30
En Latinoamérica, donde se presentan intentos de fundar identidades regionales o nacionales que ejerzan contrapeso tachykinin receptor los embates de homogeneización cultural, han aparecido diversos criterios relacionados con políticas universalistas o con el cosmopolitismo. Estos criterios sustenta
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Methods We extracted data from the WHO Health Expenditure
2019-05-30
Methods We extracted data from the WHO Health Expenditure Observatory and the Institute for Health Metrics and Evaluation\'s Financing Global Health 2015 report. We then adjusted these data by converting to a common, inflation-adjusted currency, and completed the series using multiple imputation. We
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br In a reanalysis of our results Michelle Remme and
2019-05-30
In a reanalysis of our results, Michelle Remme and colleagues (October, 2015) found that “secondary schooling might [even] be as good an HIV investment as male circumcision”, not to mention more expensive biomedical options. As Remme and colleagues rightly point out, we had excluded from our cost-
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A critical link exists between awareness of risk the presenc
2019-05-30
A critical link exists between awareness of risk, the presence of disease, and steps taken by the patient and clinician to change the natural history of disease. Chronic illnesses such as diabetes mellitus, dyslipidaemia, anaemia and a multitude of endocrinological and rheumatological diseases are r
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br Materials and methods br Results br Discussion In
2019-05-30
Materials and methods Results Discussion In recent years, it has been revealed that miRNAs are critical members of complex regulatory systems. SNPs or mutations occurring in the miRNA gene region may disturb the properties of miRNAs and result in defect in protein translation of target mRNA
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In our clinic the intracardiac
2019-05-30
In our clinic, the intracardiac electrogram recorded by the ICD showed repetitive non-reentrant ventriculoatrial synchrony (RNRVAS), which was associated with hypotension and chest discomfort (Fig. 1). We suspected that the RNRVAS caused the hypotension; therefore, we performed electrophysiologic an
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La an cdota dialoga con el
2019-05-30
La anécdota dialoga con el acto de traducción que Mier y Rodríguez realizan de la novela de Chateaubriand y, de hecho, pueden pensarse, gracias a la disposición que Mier les da en el mismo capítulo de su escrito, como actos análogos que implican la toma de posesión y desviación de la voz del extranj
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